21071703

Source:http://linkedlifedata.com/resource/pubmed/id/21071703

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0011155, umls-concept:C0086418, umls-concept:C0221099, umls-concept:C0332281, umls-concept:C0439660, umls-concept:C0679429, umls-concept:C0949860, umls-concept:C1522492
pubmed:issue	2
pubmed:dateCreated	2011-1-20
pubmed:abstractText	Platelet isoprostane 8-ISO-prostaglandin F2? (8-iso-PGF2?), a proaggregating molecule, is believed to derive from nonenzymatic oxidation of arachidonic acid. We hypothesized that NADPH is implicated in isoprostane formation and platelet activation.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9505803
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/8-epi-prostaglandin F2alpha, http://linkedlifedata.com/resource/pubmed/chemical/Aspirin, http://linkedlifedata.com/resource/pubmed/chemical/CYBB protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Calcium, http://linkedlifedata.com/resource/pubmed/chemical/Dinoprost, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Isoprostanes, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins, http://linkedlifedata.com/resource/pubmed/chemical/NADP, http://linkedlifedata.com/resource/pubmed/chemical/NADPH Oxidase, http://linkedlifedata.com/resource/pubmed/chemical/NG-Nitroarginine Methyl Ester, http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase, http://linkedlifedata.com/resource/pubmed/chemical/Platelet Aggregation Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Platelet Glycoprotein GPIIb-IIIa...
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	1524-4636
pubmed:author	pubmed-author:BartimocciaSimonaS, pubmed-author:CarnevaleRobertoR, pubmed-author:Di SantoSerenaS, pubmed-author:FinocchiAndreaA, pubmed-author:LentiLuisaL, pubmed-author:MendolicchioLoredanaL, pubmed-author:PignatelliPasqualeP, pubmed-author:PlebaniAlessandroA, pubmed-author:SanguigniValerioV, pubmed-author:SoresinaAnna RosaAR, pubmed-author:VioliFrancescoF
pubmed:issnType	Electronic
pubmed:volume	31
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	423-34
pubmed:meshHeading	pubmed-meshheading:21071703-Adult, pubmed-meshheading:21071703-Aspirin, pubmed-meshheading:21071703-Blood Platelets, pubmed-meshheading:21071703-Calcium, pubmed-meshheading:21071703-Case-Control Studies, pubmed-meshheading:21071703-Deficiency Diseases, pubmed-meshheading:21071703-Dinoprost, pubmed-meshheading:21071703-Dose-Response Relationship, Drug, pubmed-meshheading:21071703-Enzyme Inhibitors, pubmed-meshheading:21071703-Humans, pubmed-meshheading:21071703-Isoprostanes, pubmed-meshheading:21071703-Male, pubmed-meshheading:21071703-Membrane Glycoproteins, pubmed-meshheading:21071703-NADP, pubmed-meshheading:21071703-NADPH Oxidase, pubmed-meshheading:21071703-NG-Nitroarginine Methyl Ester, pubmed-meshheading:21071703-Nitric Oxide Synthase, pubmed-meshheading:21071703-Platelet Aggregation Inhibitors, pubmed-meshheading:21071703-Platelet Glycoprotein GPIIb-IIIa Complex
pubmed:year	2011
pubmed:articleTitle	Inherited human gp91phox deficiency is associated with impaired isoprostane formation and platelet dysfunction.
pubmed:affiliation	Department of Internal Medicine and Medical Specialties, I Clinica Medica, University of Rome La Sapienza, Viale del Policlinico 155, Rome, Italy.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't