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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1990-4-19
|
| pubmed:abstractText |
Lysine (LYS) and methionine (MET) transport were studied using brush border membrane vesicles from bovine jejunal and ileal tissues. Total transport of LYS and MET was divided into mediated and diffusion components. Mediated uptake was further divided into sodium (Na)-dependent and Na-independent systems. Total LYS and MET uptake by ileal brush border (BB) vesicles tended to be higher than that by jejunal BB vesicles at all concentrations evaluated but differences were significant (P less than .05) at 2.5 and 7.5 mM for LYS and 5, 12.5 and 15 mM for MET. The greater capacity of ileal BB vesicles appeared to be due to the Na-dependent component of LYS uptake and the diffusion component of MET uptake. Transporters had less affinity but higher capacity than for LYS transport in both ileal and jejunal tissue. Methionine transport was greater (P less than .05) than LYS transport in both ileal and jejunal BB vesicles when the initial amino acid concentration was 7.5 mM. But when the initial amino acid concentration was 1.25 mM, MET uptake was greater (P less than .13) than LYS uptake in jejunal, but not in ileal, BB vesicles. The relative contribution of mediated and diffusion uptake systems to total MET and LYS uptake was found to be dependent on substrate concentration. Both intestinal site and substrate concentration influenced the contributions of Na-dependent, Na-independent and diffusion systems to total methionine and lysine uptake.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0021-8812
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
68
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
504-14
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:2107161-Animals,
pubmed-meshheading:2107161-Biological Transport,
pubmed-meshheading:2107161-Cattle,
pubmed-meshheading:2107161-Diffusion,
pubmed-meshheading:2107161-Ileum,
pubmed-meshheading:2107161-Intestinal Absorption,
pubmed-meshheading:2107161-Jejunum,
pubmed-meshheading:2107161-Lysine,
pubmed-meshheading:2107161-Male,
pubmed-meshheading:2107161-Methionine,
pubmed-meshheading:2107161-Microvilli,
pubmed-meshheading:2107161-Sodium
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Lysine and methionine transport by bovine jejunal and ileal brush border membrane vesicles.
|
| pubmed:affiliation |
Dept. of Anim. Sci., Virginia Polytechnic Institute and State University, Blacksburg 24061.
|
| pubmed:publicationType |
Journal Article
|