Source:http://linkedlifedata.com/resource/pubmed/id/21067772
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2011-4-25
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pubmed:abstractText |
There is growing evidence of abnormalities of high-frequency oscillations in the gamma-range of the electroencephalography in schizophrenia. The generation of neural activity in the gamma-band was shown to be critically related to a glutamatergic and GABAergic microcircuit which is also known to be involved in the pathophysiology of schizophrenia. Recently, a reduction of the early auditory evoked gamma-band response (eGBR) in schizophrenic patients was reported. In order to investigate the possible applicability of this neurophysiological marker as an intermediate phenotype for schizophrenia, this is the main question of our investigation: Is the early eGBR decreased regarding evoked power and phase locking in first-degree relatives of patients with schizophrenia?
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1879-1379
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ltd. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
699-705
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pubmed:meshHeading |
pubmed-meshheading:21067772-Acoustic Stimulation,
pubmed-meshheading:21067772-Adult,
pubmed-meshheading:21067772-Analysis of Variance,
pubmed-meshheading:21067772-Brain Mapping,
pubmed-meshheading:21067772-Electroencephalography,
pubmed-meshheading:21067772-Evoked Potentials, Auditory,
pubmed-meshheading:21067772-Family,
pubmed-meshheading:21067772-Family Health,
pubmed-meshheading:21067772-Female,
pubmed-meshheading:21067772-Humans,
pubmed-meshheading:21067772-Male,
pubmed-meshheading:21067772-Middle Aged,
pubmed-meshheading:21067772-Reaction Time,
pubmed-meshheading:21067772-Schizophrenia,
pubmed-meshheading:21067772-Schizophrenic Psychology,
pubmed-meshheading:21067772-Time Factors,
pubmed-meshheading:21067772-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Alterations of the early auditory evoked gamma-band response in first-degree relatives of patients with schizophrenia: hints to a new intermediate phenotype.
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pubmed:affiliation |
University Medical Center Hamburg-Eppendorf, Department of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), Hamburg, Germany. g.leicht@uke.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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