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rdf:type |
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lifeskim:mentions |
umls-concept:C0017431,
umls-concept:C0026336,
umls-concept:C0026339,
umls-concept:C0039593,
umls-concept:C0087111,
umls-concept:C0262926,
umls-concept:C0683598,
umls-concept:C1527178,
umls-concept:C1705938,
umls-concept:C1963724,
umls-concept:C2004062
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pubmed:issue |
10
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pubmed:dateCreated |
2010-11-9
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pubmed:abstractText |
Although genotypic resistance testing (GRT) is recommended to guide combination antiretroviral therapy (cART), funding and/or facilities to perform GRT may not be available in low to middle income countries. Since treatment history (TH) impacts response to subsequent therapy, we investigated a set of statistical learning models to optimise cART in the absence of GRT information.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:AltmannAndréA,
pubmed-author:Di GiambenedettoSimonaS,
pubmed-author:EuResist study group,
pubmed-author:KaiserRolfR,
pubmed-author:ProsperiMattia C FMC,
pubmed-author:Rosen-ZviMichalM,
pubmed-author:SönnerborgAndersA,
pubmed-author:SchülterEugenE,
pubmed-author:SlootPeterP,
pubmed-author:StruckDanielD,
pubmed-author:VandammeAnne-MiekeAM,
pubmed-author:Virolab study group,
pubmed-author:ZazziMaurizioM,
pubmed-author:van de VijverDavid ADA
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e13753
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pubmed:dateRevised |
2011-6-8
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pubmed:meshHeading |
pubmed-meshheading:21060792-Adult,
pubmed-meshheading:21060792-Anti-HIV Agents,
pubmed-meshheading:21060792-Drug Resistance, Viral,
pubmed-meshheading:21060792-Female,
pubmed-meshheading:21060792-Genotype,
pubmed-meshheading:21060792-HIV Infections,
pubmed-meshheading:21060792-HIV-1,
pubmed-meshheading:21060792-Humans,
pubmed-meshheading:21060792-Male,
pubmed-meshheading:21060792-Middle Aged,
pubmed-meshheading:21060792-RNA, Viral,
pubmed-meshheading:21060792-ROC Curve
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pubmed:year |
2010
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pubmed:articleTitle |
Antiretroviral therapy optimisation without genotype resistance testing: a perspective on treatment history based models.
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pubmed:affiliation |
Clinic of Infectious Diseases, Catholic University of Sacred Heart, Rome, Italy. ahnven@yahoo.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Validation Studies
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