Linked Life Data

21060316

Source:http://linkedlifedata.com/resource/pubmed/id/21060316

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2010-11-16
pubmed:abstractText
Colicins are folded protein toxins that face the formidable task of translocating across one or both of the Escherichia coli cell membranes in order to induce cell death. This translocation is achieved by parasitizing host proteins. There has been much recent progress in our understanding of the early stages of colicin entry, including the binding of outer-membrane nutrient transporters and porins and the subsequent recruitment of periplasmic and inner-membrane proteins that, together, trigger translocation. As well as providing insights into how these toxins enter cells, these studies have highlighted some surprising similarities in the modes of action of the systems that colicins subvert.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1740-1534
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
843-8
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Swimming against the tide: progress and challenges in our understanding of colicin translocation.
pubmed:affiliation
Department of Biology, University of York, Wentworth Way, Heslington, YO10 5DD, UK. colin.kleanthous@york.ac.uk
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't