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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2011-1-18
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pubmed:databankReference |
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pubmed:abstractText |
The overall non-response rate to biologics remains 30-40% for patients with RA resistant to MTX. The objective of this study was to predict responsiveness to the anakinra-MTX combination by peripheral blood mononuclear cell gene profiling in order to optimize treatment choice.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1462-0332
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pubmed:author |
pubmed-author:BansardCarineC,
pubmed-author:BoyerOlivierO,
pubmed-author:DaragonAlainA,
pubmed-author:DaveauMaryvonneM,
pubmed-author:DerambureCélineC,
pubmed-author:HironMartineM,
pubmed-author:Le LoëtXavierX,
pubmed-author:LequerréThierryT,
pubmed-author:PouplinSophieS,
pubmed-author:SalierJean-PhilippeJP,
pubmed-author:TronFrançoisF,
pubmed-author:VittecoqOlivierO
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pubmed:issnType |
Electronic
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
283-92
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pubmed:meshHeading |
pubmed-meshheading:21059672-Adult,
pubmed-meshheading:21059672-Aged,
pubmed-meshheading:21059672-Antirheumatic Agents,
pubmed-meshheading:21059672-Arthritis, Rheumatoid,
pubmed-meshheading:21059672-Drug Therapy, Combination,
pubmed-meshheading:21059672-Female,
pubmed-meshheading:21059672-Gene Expression Profiling,
pubmed-meshheading:21059672-Humans,
pubmed-meshheading:21059672-Interleukin 1 Receptor Antagonist Protein,
pubmed-meshheading:21059672-Male,
pubmed-meshheading:21059672-Methotrexate,
pubmed-meshheading:21059672-Middle Aged,
pubmed-meshheading:21059672-Treatment Outcome,
pubmed-meshheading:21059672-Validation Studies as Topic
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pubmed:year |
2011
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pubmed:articleTitle |
Gene profiling predicts rheumatoid arthritis responsiveness to IL-1Ra (anakinra).
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pubmed:affiliation |
Department of Rheumatology, University of Rouen, 76031 Rouen Cedex, France.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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