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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-12-6
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pubmed:abstractText |
Colorectal cancer can be efficiently treated when found at early stages, thus the search for novel markers is of paramount importance. Since inflammation is associated with cancer progression and angiogenesis, we investigated expression of cytokines like IL-6 and other mediators that play a key role in the innate immune system, in particular toll like receptor 4 (TLR4), in the microenvironment of lesions from different stages of colon disease progression, from ulcerative colitis to adenoma and adenocarcinoma to find useful markers.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1479-5876
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pubmed:author |
pubmed-author:AlbiniAdrianaA,
pubmed-author:BarberisMassimo CMC,
pubmed-author:BertoliniValentinaV,
pubmed-author:BucciEraldo OEO,
pubmed-author:CammarotaRosariaR,
pubmed-author:GarlandaCeciliaC,
pubmed-author:GottardiOrnellaO,
pubmed-author:LaghiLuigiL,
pubmed-author:NoonanDouglas MDM,
pubmed-author:PennesiGiuseppinaG,
pubmed-author:SessaFaustoF
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
112
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pubmed:meshHeading |
pubmed-meshheading:21059221-Animals,
pubmed-meshheading:21059221-Antigens, CD,
pubmed-meshheading:21059221-Colorectal Neoplasms,
pubmed-meshheading:21059221-Cytokines,
pubmed-meshheading:21059221-Disease Models, Animal,
pubmed-meshheading:21059221-Humans,
pubmed-meshheading:21059221-Immunohistochemistry,
pubmed-meshheading:21059221-Mice,
pubmed-meshheading:21059221-Mice, Knockout,
pubmed-meshheading:21059221-Prognosis,
pubmed-meshheading:21059221-Toll-Like Receptor 4
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pubmed:year |
2010
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pubmed:articleTitle |
The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker.
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pubmed:affiliation |
Oncology Research Laboratory, Science and Technology Park, IRCCS MultiMedica, (via Fantoli 16/15), Milan, (20138), Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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