|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
12
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|
pubmed:dateCreated |
2010-11-18
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|
pubmed:abstractText |
Chronic granulomatous disease (CGD) is a genetic disorder of the phagocyte NADPH oxidase, which predisposes patients to infections and inflammatory complications, including severe colitis. Management of CGD colitis is a challenge because standard immunosuppressive therapy increases the risk of infection in already immunocompromised hosts.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Dec
|
|
pubmed:issn |
1537-6591
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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|
pubmed:day |
15
|
|
pubmed:volume |
51
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1429-34
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|
pubmed:dateRevised |
2011-6-3
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|
pubmed:meshHeading |
pubmed-meshheading:21058909-Adolescent,
pubmed-meshheading:21058909-Adult,
pubmed-meshheading:21058909-Antibodies, Monoclonal,
pubmed-meshheading:21058909-Bacterial Infections,
pubmed-meshheading:21058909-Colitis,
pubmed-meshheading:21058909-Female,
pubmed-meshheading:21058909-Granulomatous Disease, Chronic,
pubmed-meshheading:21058909-Humans,
pubmed-meshheading:21058909-Immunologic Factors,
pubmed-meshheading:21058909-Male,
pubmed-meshheading:21058909-Tumor Necrosis Factor-alpha,
pubmed-meshheading:21058909-Young Adult
|
|
pubmed:year |
2010
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|
pubmed:articleTitle |
Complications of tumor necrosis factor-? blockade in chronic granulomatous disease-related colitis.
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|
pubmed:affiliation |
Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA. guzel@mail.nih.gov
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|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, N.I.H., Intramural
|
