| pubmed-article:21052691 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21052691 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:21052691 | lifeskim:mentions | umls-concept:C0178587 | lld:lifeskim |
| pubmed-article:21052691 | lifeskim:mentions | umls-concept:C0002045 | lld:lifeskim |
| pubmed-article:21052691 | lifeskim:mentions | umls-concept:C0242995 | lld:lifeskim |
| pubmed-article:21052691 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:21052691 | lifeskim:mentions | umls-concept:C0521116 | lld:lifeskim |
| pubmed-article:21052691 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:21052691 | lifeskim:mentions | umls-concept:C1099034 | lld:lifeskim |
| pubmed-article:21052691 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:21052691 | pubmed:dateCreated | 2011-3-11 | lld:pubmed |
| pubmed-article:21052691 | pubmed:abstractText | The noninvasive evaluation of ventricular T-wave alternans (TWA) in patients with lethal ventricular arrhythmias is an important issue. In this study, we propose a novel algorithm to identify T-wave current density alternans (TWCA) using synthesized 187-channel vector-projected body surface mapping (187-ch SAVP-ECG). We recorded 10 min of 187-ch SAVP-ECG using a Mason-Likar lead system in the supine position. A recovery time (RT) dispersion map was obtained by averaging the 187-ch SAVP-ECG. The TWCA value was determined from the relative changes in the averaged current density in the T-wave zone (Tpeak ± 50 ms) for two T-wave types. We registered 20 ECG recordings from normal controls and 11 ECG recordings from nine subjects with long QT syndrome (LQT). We divided LQT syndrome subjects into two groups: group 1 provided 9 ECG recordings without visually apparent TWAs, and group 2 provided 2 ECG recordings with visually apparent TWAs. The QTc interval values in the LQT groups were higher than those in the control (515 ± 60 ms in LQT G-1, 600 ± 27 ms in LQT G-2 vs. 415 ± 19 ms in control, P < 0.001). The RTendc dispersion values among the LQT subjects were higher than those of the control subjects (48 ± 19 ms in LQT G-1, 65 ± 30 ms in LQT G-2 vs. 24 ± 10 ms in control, P < 0.01). The mean TWCA value was significantly higher in the LQT G-2 group with visually apparent TWCAs (0.5 ± 0.2% in control, 2.1 ± 1.2% in LQT G-1, and 32.3 ± 6.9% in LQT G-2). Interestingly, the two-dimensional distribution of TWCA in LQT was inhomogeneous and correlated with the distribution of increased RT dispersion. We conclude that a novel algorithm using 187-ch SAVP-ECG might provide new insights into body surface TWCA. | lld:pubmed |
| pubmed-article:21052691 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21052691 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21052691 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21052691 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21052691 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:21052691 | pubmed:issn | 1615-2573 | lld:pubmed |
| pubmed-article:21052691 | pubmed:author | pubmed-author:TakahashiShin... | lld:pubmed |
| pubmed-article:21052691 | pubmed:author | pubmed-author:HagiwaraNobuh... | lld:pubmed |
| pubmed-article:21052691 | pubmed:author | pubmed-author:KasanukiHiros... | lld:pubmed |
| pubmed-article:21052691 | pubmed:author | pubmed-author:SuzukiAtsushi... | lld:pubmed |
| pubmed-article:21052691 | pubmed:author | pubmed-author:OkabayashiHit... | lld:pubmed |
| pubmed-article:21052691 | pubmed:author | pubmed-author:ShodaMorioM | lld:pubmed |
| pubmed-article:21052691 | pubmed:author | pubmed-author:ShigaTsuyoshi... | lld:pubmed |
| pubmed-article:21052691 | pubmed:author | pubmed-author:NakaiKenjiK | lld:pubmed |
| pubmed-article:21052691 | pubmed:author | pubmed-author:TakahashiKenK | lld:pubmed |
| pubmed-article:21052691 | pubmed:author | pubmed-author:ItohManabuM | lld:pubmed |
| pubmed-article:21052691 | pubmed:author | pubmed-author:FutagawaKeisu... | lld:pubmed |
| pubmed-article:21052691 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21052691 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:21052691 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21052691 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21052691 | pubmed:pagination | 160-7 | lld:pubmed |
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| pubmed-article:21052691 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21052691 | pubmed:articleTitle | Novel algorithm for identifying T-wave current density alternans using synthesized 187-channel vector-projected body surface mapping. | lld:pubmed |
| pubmed-article:21052691 | pubmed:affiliation | Department of Internal Medicine of Dentistry, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan. knakai@iwate-med.ac.jp | lld:pubmed |
| pubmed-article:21052691 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:21052691 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
