Source:http://linkedlifedata.com/resource/pubmed/id/21052691
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
2011-3-11
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| pubmed:abstractText |
The noninvasive evaluation of ventricular T-wave alternans (TWA) in patients with lethal ventricular arrhythmias is an important issue. In this study, we propose a novel algorithm to identify T-wave current density alternans (TWCA) using synthesized 187-channel vector-projected body surface mapping (187-ch SAVP-ECG). We recorded 10 min of 187-ch SAVP-ECG using a Mason-Likar lead system in the supine position. A recovery time (RT) dispersion map was obtained by averaging the 187-ch SAVP-ECG. The TWCA value was determined from the relative changes in the averaged current density in the T-wave zone (Tpeak ± 50 ms) for two T-wave types. We registered 20 ECG recordings from normal controls and 11 ECG recordings from nine subjects with long QT syndrome (LQT). We divided LQT syndrome subjects into two groups: group 1 provided 9 ECG recordings without visually apparent TWAs, and group 2 provided 2 ECG recordings with visually apparent TWAs. The QTc interval values in the LQT groups were higher than those in the control (515 ± 60 ms in LQT G-1, 600 ± 27 ms in LQT G-2 vs. 415 ± 19 ms in control, P < 0.001). The RTendc dispersion values among the LQT subjects were higher than those of the control subjects (48 ± 19 ms in LQT G-1, 65 ± 30 ms in LQT G-2 vs. 24 ± 10 ms in control, P < 0.01). The mean TWCA value was significantly higher in the LQT G-2 group with visually apparent TWCAs (0.5 ± 0.2% in control, 2.1 ± 1.2% in LQT G-1, and 32.3 ± 6.9% in LQT G-2). Interestingly, the two-dimensional distribution of TWCA in LQT was inhomogeneous and correlated with the distribution of increased RT dispersion. We conclude that a novel algorithm using 187-ch SAVP-ECG might provide new insights into body surface TWCA.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Mar
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| pubmed:issn |
1615-2573
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| pubmed:author |
pubmed-author:FutagawaKeisukeK,
pubmed-author:HagiwaraNobuhisaN,
pubmed-author:ItohManabuM,
pubmed-author:KasanukiHiroshiH,
pubmed-author:NakaiKenjiK,
pubmed-author:OkabayashiHitoshiH,
pubmed-author:ShigaTsuyoshiT,
pubmed-author:ShodaMorioM,
pubmed-author:SuzukiAtsushiA,
pubmed-author:TakahashiKenK,
pubmed-author:TakahashiShinS
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| pubmed:issnType |
Electronic
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| pubmed:volume |
26
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
160-7
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| pubmed:meshHeading |
pubmed-meshheading:21052691-Adolescent,
pubmed-meshheading:21052691-Adult,
pubmed-meshheading:21052691-Aged,
pubmed-meshheading:21052691-Aged, 80 and over,
pubmed-meshheading:21052691-Algorithms,
pubmed-meshheading:21052691-Body Surface Potential Mapping,
pubmed-meshheading:21052691-Case-Control Studies,
pubmed-meshheading:21052691-Child, Preschool,
pubmed-meshheading:21052691-Female,
pubmed-meshheading:21052691-Heart Ventricles,
pubmed-meshheading:21052691-Humans,
pubmed-meshheading:21052691-Japan,
pubmed-meshheading:21052691-Long QT Syndrome,
pubmed-meshheading:21052691-Male,
pubmed-meshheading:21052691-Middle Aged,
pubmed-meshheading:21052691-Patient Positioning,
pubmed-meshheading:21052691-Predictive Value of Tests,
pubmed-meshheading:21052691-Signal Processing, Computer-Assisted,
pubmed-meshheading:21052691-Supine Position,
pubmed-meshheading:21052691-Time Factors,
pubmed-meshheading:21052691-Young Adult
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| pubmed:year |
2011
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| pubmed:articleTitle |
Novel algorithm for identifying T-wave current density alternans using synthesized 187-channel vector-projected body surface mapping.
|
| pubmed:affiliation |
Department of Internal Medicine of Dentistry, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate, 020-8505, Japan. knakai@iwate-med.ac.jp
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| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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