Source:http://linkedlifedata.com/resource/pubmed/id/21051388
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2011-6-9
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pubmed:abstractText |
In susceptible individuals, multiple events may trigger pulmonary vascular remodeling and pulmonary arterial hypertension (PAH). Human herpesvirus-8 (HHV-8), a ?-herpesvirus homologous with Epstein-Barr virus (EBV), was suggested to act as a "second hit" in the development of PAH in susceptible patients. Although there is indirect evidence from in vitro and animal studies in favor of a link between ?-herpesviruses and the pathophysiology of PAH, results remain controversial. Therefore, we investigated the presence of EBV and HHV-8 in the lungs of patients with PAH.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1931-3543
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1310-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21051388-Adult,
pubmed-meshheading:21051388-Case-Control Studies,
pubmed-meshheading:21051388-Female,
pubmed-meshheading:21051388-France,
pubmed-meshheading:21051388-Herpesviridae Infections,
pubmed-meshheading:21051388-Herpesvirus 4, Human,
pubmed-meshheading:21051388-Herpesvirus 8, Human,
pubmed-meshheading:21051388-Humans,
pubmed-meshheading:21051388-Hypertension, Pulmonary,
pubmed-meshheading:21051388-Lung,
pubmed-meshheading:21051388-Lung Transplantation,
pubmed-meshheading:21051388-Male,
pubmed-meshheading:21051388-Middle Aged,
pubmed-meshheading:21051388-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Human ?-herpesviruses Epstein-Barr virus and human herpesvirus-8 are not detected in the lungs of patients with severe pulmonary arterial hypertension.
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pubmed:affiliation |
Service d'Anatomie Pathologique and INSERM U563, Centre Hospitalier Universitaire Purpan, Toulouse, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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