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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-11-29
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pubmed:abstractText |
Toll-like receptors (TLRs) are a family of pattern-recognition receptors, which plays a role in eliciting innate/adaptive immune responses and developing chronic inflammation. The polymorphisms of TLRs have been associated with the risk of various autoimmune diseases, including systemic lupus erythematosus (SLE), multiple sclerosis and rheumatorid arthritis. The aim of this study was to evaluate whether TLR genes could be used as genetic markers for the development of Graves' ophthalmopathy (GO).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2350
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
154
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pubmed:meshHeading |
pubmed-meshheading:21050493-Adult,
pubmed-meshheading:21050493-Alleles,
pubmed-meshheading:21050493-Asian Continental Ancestry Group,
pubmed-meshheading:21050493-Female,
pubmed-meshheading:21050493-Genetic Markers,
pubmed-meshheading:21050493-Genetic Predisposition to Disease,
pubmed-meshheading:21050493-Graves Ophthalmopathy,
pubmed-meshheading:21050493-Haplotypes,
pubmed-meshheading:21050493-Humans,
pubmed-meshheading:21050493-Male,
pubmed-meshheading:21050493-Middle Aged,
pubmed-meshheading:21050493-Odds Ratio,
pubmed-meshheading:21050493-Polymorphism, Genetic,
pubmed-meshheading:21050493-Sex Factors,
pubmed-meshheading:21050493-Taiwan,
pubmed-meshheading:21050493-Toll-Like Receptor 4,
pubmed-meshheading:21050493-Toll-Like Receptor 9,
pubmed-meshheading:21050493-Toll-Like Receptors
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pubmed:year |
2010
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pubmed:articleTitle |
Toll-like receptor gene polymorphisms are associated with susceptibility to Graves' ophthalmopathy in Taiwan males.
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pubmed:affiliation |
Genetic Center, China Medical University Hospital, Taichung, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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