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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1990-2-16
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pubmed:abstractText |
We compared 6 patients with dorsolateral frontocentral seizures to 7 patients with temporal lobe seizures. We determined general seizure location by structural lesions in 7 patients, bilateral depth electrodes in 4, and EEG and semiology in 2. We then mapped seizure cortex and essential cortex using chronic ECoG arrays. Two ECoG patterns were similar in frontal and temporal seizures. Focal patterns were near lesions and resections. Regional patterns were distant from lesions but not associated with worse surgical outcome. "Dipolar" seizure patterns occurred in one-half of frontal patients with maps like somatosensory evoked responses, consistent with focal seizure anatomy and involvement of sensorimotor cortex. Dipole location estimates were near centers of seizure cortex determined by lesions, semiology, and outcome. Six temporal patients had focal excisions that gave significant seizure reduction in all. All frontocentral patients had focal excisions that significantly reduced seizures except in 1 patient with progressive disease. We conclude that dorsolateral frontocentral seizures have focal functional anatomy that can be predicted by ictal ECoG.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0028-3878
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
87-98
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2104966-Adult,
pubmed-meshheading:2104966-Brain Mapping,
pubmed-meshheading:2104966-Cerebral Cortex,
pubmed-meshheading:2104966-Electroencephalography,
pubmed-meshheading:2104966-Electrophysiology,
pubmed-meshheading:2104966-Epilepsies, Partial,
pubmed-meshheading:2104966-Epilepsy, Temporal Lobe,
pubmed-meshheading:2104966-Evoked Potentials, Somatosensory,
pubmed-meshheading:2104966-Frontal Lobe,
pubmed-meshheading:2104966-Humans,
pubmed-meshheading:2104966-Somatosensory Cortex
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pubmed:year |
1990
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pubmed:articleTitle |
Focal functional anatomy of dorsolateral frontocentral seizures.
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pubmed:affiliation |
Department of Neurology, School of Medicine.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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