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pubmed-article:21045736pubmed:abstractTextSpontaneously hypertensive rats (SHRs) are characterized by capillary rarefaction, which may contribute to blood pressure elevation. We hypothesized that capillary rarefaction involves a suppressed angiogenesis; renin inhibition influences anti-angiogenesis homeostasis by acting on angiopoietins; transient renin blockade reduces anti-angiogenesis thereby ameliorating long-lasting blood pressure and cardiac hypertrophy in SHRs.lld:pubmed
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pubmed-article:21045736pubmed:articleTitleRenin inhibition mitigates anti-angiogenesis in spontaneously hypertensive rats.lld:pubmed
pubmed-article:21045736pubmed:affiliationDepartment of Nephrology, Klinikum rechts der Isar, Technical University Munich, Germany.lld:pubmed
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