Linked Life Data

21044970

Source:http://linkedlifedata.com/resource/pubmed/id/21044970

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2011-3-16
pubmed:abstractText
Proinflammatory activity has been suggested as one of the psychophysiological mechanisms responsible for the health risks associated with stress and mood disorders. There have been limited studies evaluating central immune and hypothalamic- pituitary-adrenal (HPA) axis responses to experimental stress in healthy women. The current study compared, under a controlled condition, the baseline measures and biological and psychological responses to a physical stressor (lumbar puncture [LP]) of healthy women who exhibited an abnormal serum cortisol response (nonresponders [NRs]) to the LP to those of normal controls (responders [Rs]), allowing assessment of stress responsivity and the functional integrity of the feedback system of the HPA axis, sympathetic nervous system (SNS), and neuroimmune axis.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1552-4175
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
164-74
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Blunted affect is associated with hypothalamic--pituitary--adrenal axis (HPA) hypoactivity and elevated CSF-interleukin-1 beta (IL-1?) in response to lumbar puncture.
pubmed:affiliation
University of California, Los Angeles, School of Nursing, Los Angeles, CA, USA. lfitzger@sonnet.ucla.edu
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural