rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-11-22
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pubmed:abstractText |
Pandemic Vibrio parahaemolyticus has undergone rapid changes in both K- and O-antigens, making detection of outbreaks more difficult. In order to understand these rapid changes, the genetic regions encoding these antigens must be examined. In Vibrio cholerae and Vibrio vulnificus, both O-antigen and capsular polysaccharides are encoded in a single region on the large chromosome; a similar arrangement in pandemic V. parahaemolyticus would help explain the rapid serotype changes. However, previous reports on "capsule" genes are controversial. Therefore, we set out to clarify and characterize these regions in pandemic V. parahaemolyticus O3:K6 by gene deletion using a chitin based transformation strategy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2180
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
274
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pubmed:meshHeading |
pubmed-meshheading:21044320-Antigens, Bacterial,
pubmed-meshheading:21044320-Antigens, Surface,
pubmed-meshheading:21044320-Bacterial Capsules,
pubmed-meshheading:21044320-Gene Deletion,
pubmed-meshheading:21044320-Humans,
pubmed-meshheading:21044320-India,
pubmed-meshheading:21044320-Molecular Sequence Data,
pubmed-meshheading:21044320-O Antigens,
pubmed-meshheading:21044320-Pandemics,
pubmed-meshheading:21044320-Polysaccharides, Bacterial,
pubmed-meshheading:21044320-Vibrio Infections,
pubmed-meshheading:21044320-Vibrio parahaemolyticus
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pubmed:year |
2010
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pubmed:articleTitle |
Genetic analysis of the capsule polysaccharide (K antigen) and exopolysaccharide genes in pandemic Vibrio parahaemolyticus O3:K6.
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pubmed:affiliation |
Department of Pathology, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USA. yuansha.chen@pathology.ufl.edu
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pubmed:publicationType |
Journal Article
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