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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-11-24
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pubmed:abstractText |
HBO1 (histone acetyltransferase binding to ORC1) is a histone acetyltransferase (HAT) which could exert oncogenic function in breast cancer. However, the biological role and underlying mechanism of HBO1 in breast cancer remains largely unknown. In the current study, we aimed to investigate the role of HBO1 in breast cancer and uncover the underlying molecular mechanism.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Estradiol,
http://linkedlifedata.com/resource/pubmed/chemical/Estrogen Receptor alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Histone Acetyltransferases,
http://linkedlifedata.com/resource/pubmed/chemical/KAT7 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MAPK1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 1,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinase 3,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Progesterone
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pubmed:status |
MEDLINE
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pubmed:issn |
1756-9966
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pubmed:author |
pubmed-author:GuJian-xinJX,
pubmed-author:IOVAAA,
pubmed-author:LiuHai-ouHO,
pubmed-author:LiuYe-hengYH,
pubmed-author:SunLin-linLL,
pubmed-author:WangWen-zhongWZ,
pubmed-author:WuWei-binWB,
pubmed-author:WuYi-hongYH,
pubmed-author:XuJie-jieJJ,
pubmed-author:YangJun-wuJW,
pubmed-author:YunXiao-jingXJ,
pubmed-author:ZhouLeiL
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pubmed:issnType |
Electronic
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
140
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pubmed:dateRevised |
2011-10-27
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pubmed:meshHeading |
pubmed-meshheading:21040551-Blotting, Western,
pubmed-meshheading:21040551-Breast Neoplasms,
pubmed-meshheading:21040551-Cell Line, Tumor,
pubmed-meshheading:21040551-Estradiol,
pubmed-meshheading:21040551-Estrogen Receptor alpha,
pubmed-meshheading:21040551-Female,
pubmed-meshheading:21040551-Gene Expression,
pubmed-meshheading:21040551-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:21040551-Histone Acetyltransferases,
pubmed-meshheading:21040551-Humans,
pubmed-meshheading:21040551-Immunohistochemistry,
pubmed-meshheading:21040551-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:21040551-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:21040551-Receptors, Progesterone,
pubmed-meshheading:21040551-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:21040551-Signal Transduction,
pubmed-meshheading:21040551-Transfection
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pubmed:year |
2010
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pubmed:articleTitle |
Estrogen receptor ? (ER?) mediates 17?-estradiol (E2)-activated expression of HBO1.
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pubmed:affiliation |
Department of Biochemistry and Molecular Biology, Shanghai Medical College of Fudan University, Shanghai, 200032, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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