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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2010-11-2
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pubmed:abstractText |
Bipolar disorder is a debilitating psychiatric illness presenting with recurrent mania and depression. The pathophysiology of bipolar disorder is poorly understood, and molecular targets in the treatment of bipolar disorder remain to be identified. Preclinical studies have suggested that glycogen synthase kinase-3 (GSK3) is a potential therapeutic target in bipolar disorder, but evidence of abnormal GSK3 in human bipolar disorder and its response to treatment is still lacking.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1399-5618
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pubmed:author |
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pubmed:copyrightInfo |
© 2010 John Wiley and Sons A/S.
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pubmed:issnType |
Electronic
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
741-52
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pubmed:dateRevised |
2011-11-1
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pubmed:meshHeading |
pubmed-meshheading:21040291-Adult,
pubmed-meshheading:21040291-Aged,
pubmed-meshheading:21040291-Analysis of Variance,
pubmed-meshheading:21040291-Antipsychotic Agents,
pubmed-meshheading:21040291-Benzodiazepines,
pubmed-meshheading:21040291-Bipolar Disorder,
pubmed-meshheading:21040291-Electroshock,
pubmed-meshheading:21040291-Female,
pubmed-meshheading:21040291-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:21040291-Glycogen Synthase Kinase 3,
pubmed-meshheading:21040291-Humans,
pubmed-meshheading:21040291-Lithium Chloride,
pubmed-meshheading:21040291-Male,
pubmed-meshheading:21040291-Middle Aged,
pubmed-meshheading:21040291-Retrospective Studies,
pubmed-meshheading:21040291-Serine,
pubmed-meshheading:21040291-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Regulation of glycogen synthase kinase-3 during bipolar mania treatment.
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pubmed:affiliation |
Beijing Anding Hospital, Capital Medical University, 1720 Seventh Avenue South, Beijing, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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