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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2010-11-2
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pubmed:abstractText |
(i) To describe the first-order and mixed-order elimination pathways of piperacillin, (ii) to determine the between occasion variability (BOV) of pharmacokinetic parameters and (iii) to propose optimized dosage regimens.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1365-2125
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pubmed:author |
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pubmed:copyrightInfo |
© 2010 The Authors. British Journal of Clinical Pharmacology © 2010 The British Pharmacological Society.
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pubmed:issnType |
Electronic
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
682-93
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pubmed:dateRevised |
2011-11-1
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pubmed:meshHeading |
pubmed-meshheading:21039762-Adult,
pubmed-meshheading:21039762-Anti-Bacterial Agents,
pubmed-meshheading:21039762-Chromatography, High Pressure Liquid,
pubmed-meshheading:21039762-Female,
pubmed-meshheading:21039762-Humans,
pubmed-meshheading:21039762-Infusions, Intravenous,
pubmed-meshheading:21039762-Male,
pubmed-meshheading:21039762-Metabolic Clearance Rate,
pubmed-meshheading:21039762-Models, Statistical,
pubmed-meshheading:21039762-Monte Carlo Method,
pubmed-meshheading:21039762-Piperacillin,
pubmed-meshheading:21039762-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Nonlinear pharmacokinetics of piperacillin in healthy volunteers--implications for optimal dosage regimens.
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pubmed:affiliation |
IBMP -Institute for Biomedical and Pharmaceutical Research, Paul-Ehrlich-Str. 19, D-90562 Nürnberg-Heroldsberg, Germany.
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pubmed:publicationType |
Journal Article
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