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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-12-20
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pubmed:abstractText |
Neurobiological theories of addiction have highlighted disruption in stress pathways as a central feature of addictive disorders, and pharmacological treatments targeting stress mechanisms hold great promise. This study examines genetic determinants of stress-induced and cue-induced craving in heavy drinkers by testing single-nucleotide polymorphisms (SNPs) of the corticotrophin-releasing hormone binding protein (CRH-BP) gene and the mu-opioid receptor (OPRM1) gene.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1530-0277
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 by the Research Society on Alcoholism.
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pubmed:issnType |
Electronic
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
166-74
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pubmed:meshHeading |
pubmed-meshheading:21039637-Adult,
pubmed-meshheading:21039637-Affect,
pubmed-meshheading:21039637-Alcohol Drinking,
pubmed-meshheading:21039637-Alcoholism,
pubmed-meshheading:21039637-Alleles,
pubmed-meshheading:21039637-Behavior, Addictive,
pubmed-meshheading:21039637-Carrier Proteins,
pubmed-meshheading:21039637-Cues,
pubmed-meshheading:21039637-Female,
pubmed-meshheading:21039637-Humans,
pubmed-meshheading:21039637-Male,
pubmed-meshheading:21039637-Middle Aged,
pubmed-meshheading:21039637-Polymorphism, Single Nucleotide,
pubmed-meshheading:21039637-Receptors, Opioid, mu,
pubmed-meshheading:21039637-Reward,
pubmed-meshheading:21039637-Stress, Psychological,
pubmed-meshheading:21039637-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Stress-induced and cue-induced craving for alcohol in heavy drinkers: Preliminary evidence of genetic moderation by the OPRM1 and CRH-BP genes.
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pubmed:affiliation |
Department of Psychology, University of California, Los Angeles, 90095-1563, USA. lararay@psych.ucla.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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