Linked Life Data

2103844

Source:http://linkedlifedata.com/resource/pubmed/id/2103844

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-10-17
pubmed:abstractText
There is an increased risk of developing gastric carcinoma after surgery for peptic ulcer disease in humans. It is often claimed that alkaline reflux from the intestine to the stomach is a carcinogenic factor of importance in this development. In a rat model which mimics the procedures done in humans, different investigators have found an astonishingly high frequency of malignant changes. We report our findings in 19 rats operated with gastroenterostomy without resection, of which 9 developed dysplastic changes. In seven (37%) these could be classified as carcinomas or high grade dysplasia. This frequency of malignant changes is lower than that found by others. The histological classification, however, reveals substantial difficulties which are discussed. Mucin histochemistry revealed an intestinal type of cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0258-851X
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Gastric stump carcinomas in rats--a reliable gastric cancer model?
pubmed:affiliation
Department of Surgery, University Hospital Lund, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't