Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3-4
|
pubmed:dateCreated |
1991-10-15
|
pubmed:abstractText |
It has been shown that blockade of muscarinic receptors of the anterior striatum (AS) induces significant impairments in the retrieval of stored information of a passive avoidance task, trained with conventional parameters of footshock, and that the same blockade is ineffective in altering short-term memory of this task. The results of the present experimental series showed that in conditions of over-reinforcement, microinjections of scopolamine into the AS shortly after training or before retention testing of passive avoidance, do not produce memory deficits when retention is assessed 30 min, 24 h or 48 h after training. It is suggested that after an enhanced learning experience (over-reinforcement) striatal cholinergic activity is not involved in short- and long-term memory functions.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0067-9666
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
38
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
49-53
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:2103744-Animals,
pubmed-meshheading:2103744-Avoidance Learning,
pubmed-meshheading:2103744-Conditioning, Operant,
pubmed-meshheading:2103744-Corpus Striatum,
pubmed-meshheading:2103744-Male,
pubmed-meshheading:2103744-Memory Disorders,
pubmed-meshheading:2103744-Rats,
pubmed-meshheading:2103744-Rats, Inbred Strains,
pubmed-meshheading:2103744-Receptors, Muscarinic,
pubmed-meshheading:2103744-Reinforcement (Psychology),
pubmed-meshheading:2103744-Scopolamine Hydrobromide
|
pubmed:articleTitle |
Over-reinforcement protects against memory deficits induced by muscarinic blockade of the striatum.
|
pubmed:affiliation |
Laboratorio de Psicofisiología, Universidad Veracruzana, Xalapa, Ver., México.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|