Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1991-10-15
pubmed:abstractText
It has been shown that blockade of muscarinic receptors of the anterior striatum (AS) induces significant impairments in the retrieval of stored information of a passive avoidance task, trained with conventional parameters of footshock, and that the same blockade is ineffective in altering short-term memory of this task. The results of the present experimental series showed that in conditions of over-reinforcement, microinjections of scopolamine into the AS shortly after training or before retention testing of passive avoidance, do not produce memory deficits when retention is assessed 30 min, 24 h or 48 h after training. It is suggested that after an enhanced learning experience (over-reinforcement) striatal cholinergic activity is not involved in short- and long-term memory functions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0067-9666
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
49-53
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:articleTitle
Over-reinforcement protects against memory deficits induced by muscarinic blockade of the striatum.
pubmed:affiliation
Laboratorio de Psicofisiología, Universidad Veracruzana, Xalapa, Ver., México.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't