rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
2010-11-1
|
pubmed:abstractText |
Several published studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) are promising anticancer agents. This study examined the in vitro effect of O-alkylated NSAID hydroxamic acid derivatives 3a-i on cell survival for a panel of human tumour cell lines, their cytotoxicity on normal human fibroblasts and their antiviral activity.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1791-7530
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
3987-94
|
pubmed:meshHeading |
pubmed-meshheading:21036712-Animals,
pubmed-meshheading:21036712-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:21036712-Antineoplastic Agents,
pubmed-meshheading:21036712-Antiviral Agents,
pubmed-meshheading:21036712-Apoptosis,
pubmed-meshheading:21036712-Cell Cycle,
pubmed-meshheading:21036712-Cell Line, Tumor,
pubmed-meshheading:21036712-Cell Survival,
pubmed-meshheading:21036712-Drug Screening Assays, Antitumor,
pubmed-meshheading:21036712-HeLa Cells,
pubmed-meshheading:21036712-Humans,
pubmed-meshheading:21036712-Hydroxamic Acids,
pubmed-meshheading:21036712-Leukemia L1210,
pubmed-meshheading:21036712-Structure-Activity Relationship
|
pubmed:year |
2010
|
pubmed:articleTitle |
Evaluation of in vitro biological activity of O-alkylated hydroxamic derivatives of some nonsteroidal anti-inflammatory drugs.
|
pubmed:affiliation |
Department of Biotechnology, University of Rijeka, Rijeka, Croatia.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|