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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
23
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pubmed:dateCreated |
2010-12-8
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pubmed:abstractText |
Gefitinib and erlotinib can penetrate into the central nervous system (CNS) and elicit responses in patients with brain metastases (BM) from non-small cell lung cancer (NSCLC). However, there are incomplete data about their impact on the development and control of CNS metastases.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:copyrightInfo |
©2010 AACR.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5873-82
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pubmed:meshHeading |
pubmed-meshheading:21030498-Adult,
pubmed-meshheading:21030498-Aged,
pubmed-meshheading:21030498-Antineoplastic Agents,
pubmed-meshheading:21030498-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:21030498-Central Nervous System Neoplasms,
pubmed-meshheading:21030498-Disease Progression,
pubmed-meshheading:21030498-Female,
pubmed-meshheading:21030498-Genes, erbB-1,
pubmed-meshheading:21030498-Genotype,
pubmed-meshheading:21030498-Humans,
pubmed-meshheading:21030498-Lung Neoplasms,
pubmed-meshheading:21030498-Male,
pubmed-meshheading:21030498-Middle Aged,
pubmed-meshheading:21030498-Mutation,
pubmed-meshheading:21030498-Neoplasm Staging,
pubmed-meshheading:21030498-Quinazolines,
pubmed-meshheading:21030498-Randomized Controlled Trials as Topic,
pubmed-meshheading:21030498-Survival Analysis,
pubmed-meshheading:21030498-Treatment Outcome
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pubmed:year |
2010
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pubmed:articleTitle |
Development of central nervous system metastases in patients with advanced non-small cell lung cancer and somatic EGFR mutations treated with gefitinib or erlotinib.
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pubmed:affiliation |
Lowe Center for Thoracic Oncology, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Evaluation Studies,
Research Support, N.I.H., Extramural
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