Source:http://linkedlifedata.com/resource/pubmed/id/21030462
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2010-12-23
|
pubmed:abstractText |
Compared with composition-based binning algorithms, the binning accuracy and specificity of alignment-based binning algorithms is significantly higher. However, being alignment-based, the latter class of algorithms require enormous amount of time and computing resources for binning huge metagenomic datasets. The motivation was to develop a binning approach that can analyze metagenomic datasets as rapidly as composition-based approaches, but nevertheless has the accuracy and specificity of alignment-based algorithms. This article describes a hybrid binning approach (SPHINX) that achieves high binning efficiency by utilizing the principles of both 'composition'- and 'alignment'-based binning algorithms.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
1367-4811
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:day |
1
|
pubmed:volume |
27
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
22-30
|
pubmed:meshHeading |
pubmed-meshheading:21030462-Algorithms,
pubmed-meshheading:21030462-Animals,
pubmed-meshheading:21030462-Cluster Analysis,
pubmed-meshheading:21030462-Databases, Nucleic Acid,
pubmed-meshheading:21030462-Gastrointestinal Tract,
pubmed-meshheading:21030462-Metagenomics,
pubmed-meshheading:21030462-Mice,
pubmed-meshheading:21030462-Sensitivity and Specificity,
pubmed-meshheading:21030462-Sequence Alignment
|
pubmed:year |
2011
|
pubmed:articleTitle |
SPHINX--an algorithm for taxonomic binning of metagenomic sequences.
|
pubmed:affiliation |
Bio-sciences R&D Division, TCS Innovation Labs, Tata Consultancy Services Limited, Madhapur, Hyderabad, Andhra Pradesh, India.
|
pubmed:publicationType |
Journal Article,
Validation Studies
|