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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1991-9-18
|
| pubmed:abstractText |
We report findings of a study of two receptors on mononuclear cells from patients with Sjögren's syndrome (SS). The two receptors, interleukin-2 receptor (IL-2), transferrin receptor (TfR), were identified using monoclonal antibodies anti-IL-2 and OKT9. We found that the IL-2 and TfR positive cells were significantly higher on mononuclear cells (MC) from peripheral blood (PB) of patients with SS than in healthy controls. The study revealed that the IL-2 and TfR positivity reflects systemic immune activation and correlates closely with the activity of SS.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0017-6559
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
23
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
193-7
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2101803-Adult,
pubmed-meshheading:2101803-Aged,
pubmed-meshheading:2101803-Antibodies, Monoclonal,
pubmed-meshheading:2101803-Female,
pubmed-meshheading:2101803-Fluorescent Antibody Technique,
pubmed-meshheading:2101803-Humans,
pubmed-meshheading:2101803-Lymphocyte Activation,
pubmed-meshheading:2101803-Middle Aged,
pubmed-meshheading:2101803-Receptors, Interleukin-2,
pubmed-meshheading:2101803-Receptors, Transferrin,
pubmed-meshheading:2101803-Sjogren's Syndrome,
pubmed-meshheading:2101803-T-Lymphocytes
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Activation antigens in patients with Sjögren's syndrome.
|
| pubmed:affiliation |
3rd Department of Medicine, Debrecen, University Medical School, Hungary.
|
| pubmed:publicationType |
Journal Article
|