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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2011-1-20
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pubmed:abstractText |
We have previously shown that metalloproteinase 7 (MMP7) expression is increased during the acquisition of resistance to oxaliplatin in colon cancer cells. Now we have analyzed the implication of ?-catenin and EGFR pathways in the up-regulation of MMP7 in the oxaliplatin-resistant human colon cancer cell lines RHT29 and RHCT116 p53-/-, derived from the HT29 and HCT116 p53-/- cells, respectively.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 7,
http://linkedlifedata.com/resource/pubmed/chemical/Organoplatinum Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Epidermal Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/beta Catenin,
http://linkedlifedata.com/resource/pubmed/chemical/oxaliplatin,
http://linkedlifedata.com/resource/pubmed/chemical/transcription factor PEA3
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1555-8576
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4-13
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pubmed:meshHeading |
pubmed-meshheading:20980803-Antineoplastic Agents,
pubmed-meshheading:20980803-Cell Line, Tumor,
pubmed-meshheading:20980803-Cell Nucleus,
pubmed-meshheading:20980803-Colonic Neoplasms,
pubmed-meshheading:20980803-Drug Resistance, Neoplasm,
pubmed-meshheading:20980803-Enzyme Activation,
pubmed-meshheading:20980803-HCT116 Cells,
pubmed-meshheading:20980803-HT29 Cells,
pubmed-meshheading:20980803-Humans,
pubmed-meshheading:20980803-Matrix Metalloproteinase 7,
pubmed-meshheading:20980803-Organoplatinum Compounds,
pubmed-meshheading:20980803-RNA, Small Interfering,
pubmed-meshheading:20980803-Receptor, Epidermal Growth Factor,
pubmed-meshheading:20980803-Transcription Factors,
pubmed-meshheading:20980803-Transfection,
pubmed-meshheading:20980803-Up-Regulation,
pubmed-meshheading:20980803-beta Catenin
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pubmed:year |
2011
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pubmed:articleTitle |
Differential regulation of MMP7 in colon cancer cells resistant and sensitive to oxaliplatin-induced cell death.
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pubmed:affiliation |
Department of Medical Oncology, Universitat de Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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