pubmed-article:20980462 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:20980462 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
pubmed-article:20980462 | lifeskim:mentions | umls-concept:C0011860 | lld:lifeskim |
pubmed-article:20980462 | lifeskim:mentions | umls-concept:C0208355 | lld:lifeskim |
pubmed-article:20980462 | lifeskim:mentions | umls-concept:C0002716 | lld:lifeskim |
pubmed-article:20980462 | lifeskim:mentions | umls-concept:C0041538 | lld:lifeskim |
pubmed-article:20980462 | lifeskim:mentions | umls-concept:C0011155 | lld:lifeskim |
pubmed-article:20980462 | lifeskim:mentions | umls-concept:C1421309 | lld:lifeskim |
pubmed-article:20980462 | lifeskim:mentions | umls-concept:C1157980 | lld:lifeskim |
pubmed-article:20980462 | lifeskim:mentions | umls-concept:C0127400 | lld:lifeskim |
pubmed-article:20980462 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:20980462 | pubmed:dateCreated | 2011-1-3 | lld:pubmed |
pubmed-article:20980462 | pubmed:abstractText | The islet in type 2 diabetes is characterized by ?-cell apoptosis, ?-cell endoplasmic reticulum stress, and islet amyloid deposits derived from islet amyloid polypeptide (IAPP). Toxic oligomers of IAPP form intracellularly in ?-cells in humans with type 2 diabetes, suggesting impaired clearance of misfolded proteins. In this study, we investigated whether human-IAPP (h-IAPP) disrupts the endoplasmic reticulum-associated degradation/ubiquitin/proteasome system. | lld:pubmed |
pubmed-article:20980462 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20980462 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20980462 | pubmed:language | eng | lld:pubmed |
pubmed-article:20980462 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20980462 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:20980462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20980462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20980462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20980462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20980462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20980462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20980462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20980462 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:20980462 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:20980462 | pubmed:month | Jan | lld:pubmed |
pubmed-article:20980462 | pubmed:issn | 1939-327X | lld:pubmed |
pubmed-article:20980462 | pubmed:author | pubmed-author:ButlerPeter... | lld:pubmed |
pubmed-article:20980462 | pubmed:author | pubmed-author:RizzaRobert... | lld:pubmed |
pubmed-article:20980462 | pubmed:author | pubmed-author:HuangChang-ji... | lld:pubmed |
pubmed-article:20980462 | pubmed:author | pubmed-author:ButlerAlexand... | lld:pubmed |
pubmed-article:20980462 | pubmed:author | pubmed-author:GurloTatyanaT | lld:pubmed |
pubmed-article:20980462 | pubmed:author | pubmed-author:CostesSafiaS | lld:pubmed |
pubmed-article:20980462 | pubmed:author | pubmed-author:DavalMarieM | lld:pubmed |
pubmed-article:20980462 | pubmed:author | pubmed-author:MatveyenkoAle... | lld:pubmed |
pubmed-article:20980462 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:20980462 | pubmed:volume | 60 | lld:pubmed |
pubmed-article:20980462 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:20980462 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:20980462 | pubmed:pagination | 227-38 | lld:pubmed |
pubmed-article:20980462 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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pubmed-article:20980462 | pubmed:meshHeading | pubmed-meshheading:20980462... | lld:pubmed |
pubmed-article:20980462 | pubmed:year | 2011 | lld:pubmed |
pubmed-article:20980462 | pubmed:articleTitle | ?-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency. | lld:pubmed |
pubmed-article:20980462 | pubmed:affiliation | Larry Hillblom Islet Research Center, University of California, Los Angeles, USA. scostes@mednet.ucla.edu | lld:pubmed |
pubmed-article:20980462 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:20980462 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
pubmed-article:20980462 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
entrez-gene:7345 | entrezgene:pubmed | pubmed-article:20980462 | lld:entrezgene |
http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:20980462 | lld:entrezgene |