rdf:type |
|
lifeskim:mentions |
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pubmed:issue |
9
|
pubmed:dateCreated |
2010-10-26
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pubmed:abstractText |
Cervical intraepithelial neoplasia (CIN) is associated with genital human papillomavirus (HPV) infection and represents the precursor of cervical cancer. Established ablative treatment methods may cause substantial complications in following pregnancies including premature delivery and the birth of low-weight babies. Photodynamic therapy (PDT) of CIN using esters of 5-aminolevulinic acid (5-ALA) represents a promising alternative. However, it has not been analyzed yet if the PDT itself leads to sustained damage of the cervical tissue. This study aims at evaluating the effect of hexylaminolevulinate (HAL) and methylaminolevulinate (MAL) PDT on cervical tissue.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
1096-9101
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pubmed:author |
|
pubmed:copyrightInfo |
© 2010 Wiley-Liss, Inc.
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pubmed:issnType |
Electronic
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pubmed:volume |
42
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
624-30
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pubmed:meshHeading |
pubmed-meshheading:20976802-Administration, Topical,
pubmed-meshheading:20976802-Adult,
pubmed-meshheading:20976802-Aminolevulinic Acid,
pubmed-meshheading:20976802-Cervical Intraepithelial Neoplasia,
pubmed-meshheading:20976802-Cohort Studies,
pubmed-meshheading:20976802-Double-Blind Method,
pubmed-meshheading:20976802-Epithelium,
pubmed-meshheading:20976802-Female,
pubmed-meshheading:20976802-Humans,
pubmed-meshheading:20976802-Middle Aged,
pubmed-meshheading:20976802-Photochemotherapy,
pubmed-meshheading:20976802-Photosensitizing Agents,
pubmed-meshheading:20976802-Tumor Markers, Biological,
pubmed-meshheading:20976802-Uterine Cervical Neoplasms,
pubmed-meshheading:20976802-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Effects of photodynamic therapy using topical applied hexylaminolevulinate and methylaminolevulinate upon the integrity of cervical epithelium.
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pubmed:affiliation |
University Women's Clinic, Hannover Medical School, 30625 Hannover, Germany. soergel.philipp@mh-hannover.de
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
|