Dendritic cells capture antigens through PRRs and modulate adaptive immune responses. The type of adaptive immune T cell response generated is dependent upon the type of PRR activated by the microbes. Dectin-1 is a C-type lectin receptor present on dendritic cells.
Division of Basic and Clinical Immunology, Department of Medicine, University of California Irvine, Irvine, California, United States of America. aagrawal@uci.edu