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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2011-3-23
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pubmed:abstractText |
Mutations in Toll-like receptor (TLR)-4 have been associated with the hyporesponsiveness of macrophages to lipopolysaccharide, possibly reducing the risk of acute graft-versus-host disease (GVHD). However, TLR-4 mutations may also increase the risk of intestinal damage and microbial infection, thereby accelerating acute GVHD.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation...,
http://linkedlifedata.com/resource/pubmed/chemical/CD68 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2,
http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone,
http://linkedlifedata.com/resource/pubmed/chemical/HGF protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Hepatocyte Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides,
http://linkedlifedata.com/resource/pubmed/chemical/Ptgs2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tlr4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 4,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1534-6080
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
27
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1063-70
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pubmed:meshHeading |
pubmed-meshheading:20975627-Acute Disease,
pubmed-meshheading:20975627-Animals,
pubmed-meshheading:20975627-Antigens, CD,
pubmed-meshheading:20975627-Antigens, Differentiation, Myelomonocytic,
pubmed-meshheading:20975627-Apoptosis,
pubmed-meshheading:20975627-Base Sequence,
pubmed-meshheading:20975627-Cell Proliferation,
pubmed-meshheading:20975627-Cyclooxygenase 2,
pubmed-meshheading:20975627-DNA Primers,
pubmed-meshheading:20975627-Dinoprostone,
pubmed-meshheading:20975627-Female,
pubmed-meshheading:20975627-Gene Expression,
pubmed-meshheading:20975627-Graft vs Host Disease,
pubmed-meshheading:20975627-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:20975627-Hepatocyte Growth Factor,
pubmed-meshheading:20975627-Immunity, Innate,
pubmed-meshheading:20975627-Intestines,
pubmed-meshheading:20975627-Lipopolysaccharides,
pubmed-meshheading:20975627-Liver,
pubmed-meshheading:20975627-Macrophages,
pubmed-meshheading:20975627-Mice,
pubmed-meshheading:20975627-Mice, Inbred C3H,
pubmed-meshheading:20975627-Mice, Inbred C57BL,
pubmed-meshheading:20975627-Models, Immunological,
pubmed-meshheading:20975627-Mutation,
pubmed-meshheading:20975627-Neutrophils,
pubmed-meshheading:20975627-RNA, Messenger,
pubmed-meshheading:20975627-Toll-Like Receptor 4,
pubmed-meshheading:20975627-Transplantation, Homologous,
pubmed-meshheading:20975627-Tumor Necrosis Factor-alpha
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pubmed:year |
2010
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pubmed:articleTitle |
The protective role of host Toll-like receptor-4 in acute graft-versus-host disease.
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pubmed:affiliation |
Division of Rheumatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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