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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
17
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pubmed:dateCreated |
2010-10-26
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pubmed:abstractText |
Calcitonin gene-related peptide (CGRP) plays a fundamental role in the pathophysiology of neurovascular headaches. CGRP infusion causes headache and dilation of cranial vessels. However, it is unknown to what extent CGRP-induced vasodilation contributes to immediate head pain and whether the migraine-specific abortive drug sumatriptan, a 5-hydroxytryptamine 1B/1D agonist, inhibits CGRP-induced immediate vasodilation and headache.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1526-632X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
26
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1520-6
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pubmed:dateRevised |
2011-8-25
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pubmed:meshHeading |
pubmed-meshheading:20975053-Adult,
pubmed-meshheading:20975053-Area Under Curve,
pubmed-meshheading:20975053-Blood Pressure,
pubmed-meshheading:20975053-Calcitonin Gene-Related Peptide,
pubmed-meshheading:20975053-Confidence Intervals,
pubmed-meshheading:20975053-Double-Blind Method,
pubmed-meshheading:20975053-Drug Interactions,
pubmed-meshheading:20975053-Female,
pubmed-meshheading:20975053-Headache,
pubmed-meshheading:20975053-Humans,
pubmed-meshheading:20975053-Magnetic Resonance Angiography,
pubmed-meshheading:20975053-Magnetic Resonance Imaging,
pubmed-meshheading:20975053-Male,
pubmed-meshheading:20975053-Meningeal Arteries,
pubmed-meshheading:20975053-Middle Cerebral Artery,
pubmed-meshheading:20975053-Sumatriptan,
pubmed-meshheading:20975053-Vasoconstrictor Agents,
pubmed-meshheading:20975053-Vasodilation,
pubmed-meshheading:20975053-Vasodilator Agents,
pubmed-meshheading:20975053-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Dilation by CGRP of middle meningeal artery and reversal by sumatriptan in normal volunteers.
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pubmed:affiliation |
Danish Headache Center and Department of Neurology, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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