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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2011-3-7
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pubmed:abstractText |
Ulcerative colitis is associated with increased interleukin 13 (IL-13) production by natural killer T cells. Taking advantage of the inhibitory actions of interferon ? on IL-13 expression, this proof-of-concept study aimed to show that decreasing IL-13 production is associated with clinical improvement of ulcerative colitis symptoms.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1468-3288
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
60
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
449-55
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pubmed:meshHeading |
pubmed-meshheading:20971977-Adolescent,
pubmed-meshheading:20971977-Adult,
pubmed-meshheading:20971977-Aged,
pubmed-meshheading:20971977-CD4-Positive T-Lymphocytes,
pubmed-meshheading:20971977-Cells, Cultured,
pubmed-meshheading:20971977-Colitis, Ulcerative,
pubmed-meshheading:20971977-Cytokines,
pubmed-meshheading:20971977-Female,
pubmed-meshheading:20971977-Follow-Up Studies,
pubmed-meshheading:20971977-Gastrointestinal Agents,
pubmed-meshheading:20971977-Humans,
pubmed-meshheading:20971977-Interferon-beta,
pubmed-meshheading:20971977-Interleukin-13,
pubmed-meshheading:20971977-Male,
pubmed-meshheading:20971977-Middle Aged,
pubmed-meshheading:20971977-Treatment Outcome,
pubmed-meshheading:20971977-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
Suppression of inflammation in ulcerative colitis by interferon-?-1a is accompanied by inhibition of IL-13 production.
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pubmed:affiliation |
Mucosal Immunity Section, Laboratory of Host Defense, NIAID, NIH, Bethesda, Maryland, USA. pmannon@uab.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, N.I.H., Extramural,
Research Support, N.I.H., Intramural
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