Linked Life Data

20971627

Source:http://linkedlifedata.com/resource/pubmed/id/20971627

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2011-1-3
pubmed:abstractText
A miniature multi-sample chip for protein detection with a bench-top magnetic resonance imager was created on the basis of magnetic relaxation switches. The chip was assessed with two protein systems. Both qualitative and quantitative results for the target proteins were obtained by image analysis and relaxation time measurement, respectively. The detection of prostate specific antigen, the serum marker of human prostate cancer, showed a linear concentration range of 17.3-43.2 ng mL(-1) and a detection limit of 13.7 ng mL(-1). As proof of concept, the analysis of 18 samples with a volume of 6.37 ?L each was completed in 26 min by this chip. This technique may become an easy and efficient approach for rapid and high-throughput protein assay and protein-protein interaction screening.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1873-4235
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 Elsevier B.V. All rights reserved.
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2258-63
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
A miniature chip for protein detection based on magnetic relaxation switches.
pubmed:affiliation
Department of Chemistry & Institutes of Biomedical Sciences, Fudan University, 220# Handan Road, Shanghai 200433, PR China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't