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rdf:type |
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lifeskim:mentions |
umls-concept:C0005953,
umls-concept:C0162574,
umls-concept:C0205263,
umls-concept:C0282554,
umls-concept:C0600210,
umls-concept:C1257975,
umls-concept:C1327413,
umls-concept:C1366876,
umls-concept:C1514485,
umls-concept:C1704259,
umls-concept:C1705987,
umls-concept:C1833235,
umls-concept:C1879547
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pubmed:dateCreated |
2010-11-18
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pubmed:abstractText |
Advanced glycation products (AGEs), as endogenous inflammatory mediator, compromise the physiological function of mesenchymal stem cells (MSCs). MSCs have a potential role in cell replacement therapy in acute myocardial infarction and ischemic cardiomyopathy. However, mechanisms of AGEs on MSCs are still not unveiled.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD3,
http://linkedlifedata.com/resource/pubmed/chemical/Ccl2 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL4,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Glycosylation End Products, Advanced,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1beta,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinase Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Reactive Oxygen Species,
http://linkedlifedata.com/resource/pubmed/chemical/Serum Albumin, Bovine,
http://linkedlifedata.com/resource/pubmed/chemical/advanced glycation end...,
http://linkedlifedata.com/resource/pubmed/chemical/p38 Mitogen-Activated Protein...
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pubmed:status |
MEDLINE
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pubmed:issn |
1475-2840
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
66
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pubmed:meshHeading |
pubmed-meshheading:20969783-Animals,
pubmed-meshheading:20969783-Antigens, CD3,
pubmed-meshheading:20969783-Bone Marrow Cells,
pubmed-meshheading:20969783-Cell Movement,
pubmed-meshheading:20969783-Cell Proliferation,
pubmed-meshheading:20969783-Cells, Cultured,
pubmed-meshheading:20969783-Chemokine CCL2,
pubmed-meshheading:20969783-Chemokine CCL4,
pubmed-meshheading:20969783-Chemokines,
pubmed-meshheading:20969783-Cytokines,
pubmed-meshheading:20969783-Enzyme Activation,
pubmed-meshheading:20969783-Gene Expression Profiling,
pubmed-meshheading:20969783-Glycosylation End Products, Advanced,
pubmed-meshheading:20969783-Interleukin-1beta,
pubmed-meshheading:20969783-Male,
pubmed-meshheading:20969783-Mesenchymal Stem Cells,
pubmed-meshheading:20969783-Phosphorylation,
pubmed-meshheading:20969783-Protein Kinase Inhibitors,
pubmed-meshheading:20969783-Rats,
pubmed-meshheading:20969783-Rats, Sprague-Dawley,
pubmed-meshheading:20969783-Reactive Oxygen Species,
pubmed-meshheading:20969783-Serum Albumin, Bovine,
pubmed-meshheading:20969783-Signal Transduction,
pubmed-meshheading:20969783-Time Factors,
pubmed-meshheading:20969783-Up-Regulation,
pubmed-meshheading:20969783-p38 Mitogen-Activated Protein Kinases
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pubmed:year |
2010
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pubmed:articleTitle |
Advanced glycation end products induce chemokine/cytokine production via activation of p38 pathway and inhibit proliferation and migration of bone marrow mesenchymal stem cells.
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pubmed:affiliation |
Department of Cardiology, Ruijin Hospital, Jiaotong University School of Medicine, Shanghai, P.R. China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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