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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2010-11-11
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pubmed:abstractText |
NORE1 (RASSF5) is a newly described member of the RASSF family with Ras effector function. NORE1 expression is frequently inactivated by aberrant promoter hypermethylation in many human cancers, suggesting that NORE1 might be a putative tumor suppressor. However, expression and mutation status of NORE1 and its implication in colorectal tumorigenesis has not been evaluated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
pubmed-author:ChiSung-GilSG,
pubmed-author:HaTae-KyuTK,
pubmed-author:HwangboYoungY,
pubmed-author:JangJae YoungJY,
pubmed-author:JeongSeong-InSI,
pubmed-author:KangMin-JuMJ,
pubmed-author:KimHyo JongHJ,
pubmed-author:LeeChang KyunCK,
pubmed-author:LeeJin-HeeJH,
pubmed-author:LeeKil YeonKY,
pubmed-author:LeeMin-GooMG,
pubmed-author:RyuByung-KyuBK,
pubmed-author:ShimJae-JunJJ
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
577
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pubmed:meshHeading |
pubmed-meshheading:20969767-Apoptosis,
pubmed-meshheading:20969767-Caco-2 Cells,
pubmed-meshheading:20969767-Cell Line, Tumor,
pubmed-meshheading:20969767-Cell Proliferation,
pubmed-meshheading:20969767-Colorectal Neoplasms,
pubmed-meshheading:20969767-CpG Islands,
pubmed-meshheading:20969767-DNA Methylation,
pubmed-meshheading:20969767-DNA Mutational Analysis,
pubmed-meshheading:20969767-Disease Progression,
pubmed-meshheading:20969767-Epigenesis, Genetic,
pubmed-meshheading:20969767-Flow Cytometry,
pubmed-meshheading:20969767-Genes, Tumor Suppressor,
pubmed-meshheading:20969767-Humans,
pubmed-meshheading:20969767-Monomeric GTP-Binding Proteins,
pubmed-meshheading:20969767-Sequence Analysis, DNA
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pubmed:year |
2010
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pubmed:articleTitle |
Epigenetic inactivation of the NORE1 gene correlates with malignant progression of colorectal tumors.
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pubmed:affiliation |
Division of Gastroenterology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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