Linked Life Data

20969732

Source:http://linkedlifedata.com/resource/pubmed/id/20969732

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-12-14
pubmed:abstractText
The apical membrane anion exchanger putative anion transporter-1 (Pat-1) is expressed at significant levels in the lower villus epithelium of murine duodenum. However, previous studies of Cl(?)/HCO?(?) exchange in the lower villus have failed to demonstrate Pat-1 function. Those studies routinely included luminal glucose which induces Na(+) -coupled glucose transport and acidifies the villus epithelium. Since Pat-1 has been proposed to be an electrogenic 1Cl(?)/2HCO?(?) exchanger, membrane depolarization or cell acidification during glucose transport may obscure Pat-1 activity. Therefore, we investigated the effects of luminal glucose on Cl(?)(IN)/HCO?(?) (OUT) exchange activity in the lower villus epithelium.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1748-1716
pubmed:author
pubmed:copyrightInfo
© 2010 The Authors. Acta Physiologica © 2010 Scandinavian Physiological Society.
pubmed:issnType
Electronic
pubmed:volume
201
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
21-31
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Functional activity of Pat-1 (Slc26a6) Cl(?)/HCO?(?) exchange in the lower villus epithelium of murine duodenum.
pubmed:affiliation
Dalton Cardiovascular Research Center, University of Missouri, Columbia, 65211, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural