|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2010-12-16
|
|
pubmed:abstractText |
Atherosclerosis encompasses a conspicuously maladaptive inflammatory response that might involve innate immunity. Here, we compared the role of Toll-like receptor 4 (TLR4) with that of TLR2 in intimal foam cell accumulation and inflammation in apolipoprotein E (ApoE) knockout (KO) mice in vivo and determined potential mechanisms of upstream activation and downstream action.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acat1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Acetyl-CoA C-Acetyltransferase,
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E,
http://linkedlifedata.com/resource/pubmed/chemical/Ccl2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Inflammation Mediators,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1alpha,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tlr2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Tlr4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 2,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 4,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Cell Adhesion Molecule-1
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
1524-4636
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
31
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
50-7
|
|
pubmed:dateRevised |
2011-9-26
|
|
pubmed:meshHeading |
pubmed-meshheading:20966403-Acetyl-CoA C-Acetyltransferase,
pubmed-meshheading:20966403-Animals,
pubmed-meshheading:20966403-Aorta, Thoracic,
pubmed-meshheading:20966403-Aortic Diseases,
pubmed-meshheading:20966403-Apolipoproteins E,
pubmed-meshheading:20966403-Atherosclerosis,
pubmed-meshheading:20966403-Chemokine CCL2,
pubmed-meshheading:20966403-Cholesterol,
pubmed-meshheading:20966403-Disease Models, Animal,
pubmed-meshheading:20966403-Female,
pubmed-meshheading:20966403-Foam Cells,
pubmed-meshheading:20966403-Gene Expression Regulation,
pubmed-meshheading:20966403-Inflammation Mediators,
pubmed-meshheading:20966403-Interleukin-1alpha,
pubmed-meshheading:20966403-Male,
pubmed-meshheading:20966403-Mice,
pubmed-meshheading:20966403-Mice, Knockout,
pubmed-meshheading:20966403-Myocytes, Smooth Muscle,
pubmed-meshheading:20966403-RNA, Messenger,
pubmed-meshheading:20966403-Signal Transduction,
pubmed-meshheading:20966403-Time Factors,
pubmed-meshheading:20966403-Toll-Like Receptor 2,
pubmed-meshheading:20966403-Toll-Like Receptor 4,
pubmed-meshheading:20966403-Triglycerides,
pubmed-meshheading:20966403-Vascular Cell Adhesion Molecule-1
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
Role of toll-like receptor 4 in intimal foam cell accumulation in apolipoprotein E-deficient mice.
|
|
pubmed:affiliation |
Tufts Medical Center, Boston, MA 02111, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
