Source:http://linkedlifedata.com/resource/pubmed/id/20962448
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
20
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pubmed:dateCreated |
2010-10-21
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pubmed:abstractText |
A 26-year-old man was hospitalized with a 1-month history of fever. Cervical lymph node biopsy showed necrosis in the paracortical area with abundant nuclear debris and proliferation of histiocytes. A diagnosis of histiocytic necrotizing lymphadenitis (HNL) (Kikuchi's disease) was made. He received methylprednisolone pulse therapy (MPT) (0.5 g/day for 3 days) without maintenance therapy and experienced dramatic improvement. We also used MPT for another 12 cases of HNL. All patients became afebrile within 1 day without adverse events. Four patients relapsed after the initial MPT, but only 1 patient relapsed during the following year. Our results suggest that MPT is warranted in HNL patients with prolonged fever.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1349-7235
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2267-70
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pubmed:meshHeading |
pubmed-meshheading:20962448-Adolescent,
pubmed-meshheading:20962448-Adult,
pubmed-meshheading:20962448-Anti-Inflammatory Agents,
pubmed-meshheading:20962448-Drug Evaluation,
pubmed-meshheading:20962448-Female,
pubmed-meshheading:20962448-Fever,
pubmed-meshheading:20962448-Histiocytic Necrotizing Lymphadenitis,
pubmed-meshheading:20962448-Humans,
pubmed-meshheading:20962448-Lymph Nodes,
pubmed-meshheading:20962448-Male,
pubmed-meshheading:20962448-Methylprednisolone,
pubmed-meshheading:20962448-Middle Aged,
pubmed-meshheading:20962448-Pulse Therapy, Drug,
pubmed-meshheading:20962448-Recurrence,
pubmed-meshheading:20962448-Retrospective Studies,
pubmed-meshheading:20962448-Young Adult
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pubmed:year |
2010
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pubmed:articleTitle |
Treatment of histiocytic necrotizing lymphadenitis (Kikuchi's disease) with prolonged fever by a single course of methylprednisolone pulse therapy without maintenance therapy: experience with 13 cases.
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pubmed:affiliation |
Department of Internal Medicine, Osaka City General Hospital. kmyoshi@rr.iij4u.or.jp
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pubmed:publicationType |
Journal Article
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