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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0032214,
umls-concept:C0035820,
umls-concept:C0152021,
umls-concept:C0162638,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C0225828,
umls-concept:C0332162,
umls-concept:C0392756,
umls-concept:C1825843,
umls-concept:C2911684
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pubmed:issue |
11
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pubmed:dateCreated |
2010-10-29
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pubmed:abstractText |
The Cardiac ? actin 1 gene (ACTC1) has been related to familial atrial septal defects. This study was set to explore a potential role of this gene in the formation of sporadic congenital heart disease (CHD).
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1347-4820
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2410-8
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pubmed:dateRevised |
2011-2-18
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pubmed:meshHeading |
pubmed-meshheading:20962418-Actins,
pubmed-meshheading:20962418-Age Factors,
pubmed-meshheading:20962418-Animals,
pubmed-meshheading:20962418-Apoptosis,
pubmed-meshheading:20962418-Blotting, Western,
pubmed-meshheading:20962418-Case-Control Studies,
pubmed-meshheading:20962418-Caspase 3,
pubmed-meshheading:20962418-Cell Line,
pubmed-meshheading:20962418-Child, Preschool,
pubmed-meshheading:20962418-China,
pubmed-meshheading:20962418-Down-Regulation,
pubmed-meshheading:20962418-Female,
pubmed-meshheading:20962418-Gene Expression Regulation, Developmental,
pubmed-meshheading:20962418-Gestational Age,
pubmed-meshheading:20962418-Heart Defects, Congenital,
pubmed-meshheading:20962418-Humans,
pubmed-meshheading:20962418-Immunohistochemistry,
pubmed-meshheading:20962418-In Situ Nick-End Labeling,
pubmed-meshheading:20962418-Infant,
pubmed-meshheading:20962418-Infant, Newborn,
pubmed-meshheading:20962418-Male,
pubmed-meshheading:20962418-Myocytes, Cardiac,
pubmed-meshheading:20962418-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:20962418-RNA, Messenger,
pubmed-meshheading:20962418-RNA Interference,
pubmed-meshheading:20962418-Rats,
pubmed-meshheading:20962418-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:20962418-Transfection
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pubmed:year |
2010
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pubmed:articleTitle |
Reduced ACTC1 expression might play a role in the onset of congenital heart disease by inducing cardiomyocyte apoptosis.
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pubmed:affiliation |
Department of Pediatrics, The First Affiliated Hospital of China Medical University, Shenyang, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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