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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2010-11-4
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pubmed:abstractText |
The success of many pathogens relies on their ability to circumvent the innate and adaptive immune defenses. How bacterial pathogens subvert adaptive immune defenses is not clear. Cholesterol-dependent cytolysins (CDCs) represent an expansive family of homologous pore-forming toxins that are produced by more than 20 gram-positive bacterial species. Listeriolysin O (LLO), a prototype CDC, is the main virulence factor of Listeria monocytogenes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1537-6613
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
202
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1698-707
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pubmed:meshHeading |
pubmed-meshheading:20961225-Animals,
pubmed-meshheading:20961225-Bacterial Toxins,
pubmed-meshheading:20961225-CD4-Positive T-Lymphocytes,
pubmed-meshheading:20961225-Disease Models, Animal,
pubmed-meshheading:20961225-Flow Cytometry,
pubmed-meshheading:20961225-Gene Expression,
pubmed-meshheading:20961225-Heat-Shock Proteins,
pubmed-meshheading:20961225-Hemolysin Proteins,
pubmed-meshheading:20961225-Listeria monocytogenes,
pubmed-meshheading:20961225-Mice,
pubmed-meshheading:20961225-Mice, Inbred C57BL,
pubmed-meshheading:20961225-Microarray Analysis,
pubmed-meshheading:20961225-Receptors, Antigen, T-Cell,
pubmed-meshheading:20961225-Specific Pathogen-Free Organisms
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pubmed:year |
2010
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pubmed:articleTitle |
Listeria monocytogenes induces T cell receptor unresponsiveness through pore-forming toxin listeriolysin O.
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pubmed:affiliation |
Molecular Immunology, Helmholtz Center for Infection Research, Braunschweig, Germany. nelson.gekara@mims.umu.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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