Linked Life Data

2095899

Source:http://linkedlifedata.com/resource/pubmed/id/2095899

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-7-15
pubmed:abstractText
We have evaluated with Western blotting the serologic response of 144 patients with acute brucellosis and 62 healthy controls to identify a useful antibody pattern to confirm the diagnosis of acute brucellosis. The antigen that we used was a protein extract of whole cells of the strain 115 (rough) of B. melitensis. Patients sera were obtained at the time of diagnosis and before the start of specific therapy. There was antibody response to 21 protein bands. The molecular weights (MW) and frequencies of the most significant bands were the following: 85 Kd (60.4%), 70 Kd (54.1%), 53 Kd (63.9%), 50 Kd (65.3%), 47 Kd (71.5%), 41 Kd (74.3%), 38 Kd (68.7%), 33 Kd (56.2%), 28 Kd (52.8%). At the time of diagnosis, 90.3% of the patients with acute brucellosis had antibody response to 2 or more protein bands of Mw of 47 Kd, 41 Kd, 38 Kd and 33 Kd. In none of the 62 negative control sera there was a response to more than one of the mentioned bands.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0213-005X
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
15-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[Pattern of antibodies in acute human brucellosis defined by Western blotting].
pubmed:affiliation
Servicio di Microbiología, Hospital Virgen de las Nieves, Granada.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't