Linked Life Data

20953552

Source:http://linkedlifedata.com/resource/pubmed/id/20953552

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2010-10-18
pubmed:abstractText
In the relationships between host and parasites, there is a cross-talk that involves diverse mechanisms developed by two different genetic systems during years of evolution. On the one hand, immunocompetent hosts have developed effective innate and acquired immune responses that are used to restrict or avoid parasitism. On the other hand, parasites evade the immune response, expressing different antigens on their surface or by using other specific mechanisms, such as nutrient depletion. In this review, we analyze the survival mechanisms used by the protozoan parasite Giardia lamblia during infection. In particular, we examine the multiple roles played by the enzyme arginine deiminase during colonization of the gut, also involving the parasite's mechanism of antigenic variation. Potential drug targets for the treatment of giardiasis are also discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1537-744X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2019-31
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
A lesson in survival, by Giardia lamblia.
pubmed:affiliation
Instituto de Investigación Médica Mercedes y Martín Ferreyra, INIMEC – CONICET, Córdoba. Argentina. aropolo@immf.uncor.edu
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't