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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2010-11-30
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pubmed:abstractText |
Hepatocellular carcinoma (HCC) is associated with a high potential for metastasis and disease recurrence, even after surgical resection. The cancer stem cell (CSC) hypothesis proposes that CSCs are responsible for chemo-resistance, recurrence, and metastasis. Dysadherin is a prognostic indicator of metastasis and poor survival in many different cancer types. In this study, we investigated the possible link between dysadherin and CSC in HCC.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ABCB1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/FXYD5 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/P-Glycoprotein,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
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pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
122-31
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pubmed:meshHeading |
pubmed-meshheading:20952084-Animals,
pubmed-meshheading:20952084-Apoptosis,
pubmed-meshheading:20952084-Carcinoma, Hepatocellular,
pubmed-meshheading:20952084-Cell Line, Tumor,
pubmed-meshheading:20952084-Cell Proliferation,
pubmed-meshheading:20952084-Gene Expression Profiling,
pubmed-meshheading:20952084-Gene Knockdown Techniques,
pubmed-meshheading:20952084-Humans,
pubmed-meshheading:20952084-Liver Neoplasms,
pubmed-meshheading:20952084-Membrane Glycoproteins,
pubmed-meshheading:20952084-Mice,
pubmed-meshheading:20952084-Mice, Inbred NOD,
pubmed-meshheading:20952084-Mice, SCID,
pubmed-meshheading:20952084-Neoplasm Proteins,
pubmed-meshheading:20952084-Neoplastic Stem Cells,
pubmed-meshheading:20952084-P-Glycoprotein,
pubmed-meshheading:20952084-Prognosis,
pubmed-meshheading:20952084-RNA, Messenger,
pubmed-meshheading:20952084-RNA, Neoplasm,
pubmed-meshheading:20952084-RNA Interference,
pubmed-meshheading:20952084-Spheroids, Cellular,
pubmed-meshheading:20952084-Transfection,
pubmed-meshheading:20952084-Tumor Markers, Biological,
pubmed-meshheading:20952084-Tumor Stem Cell Assay
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pubmed:year |
2011
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pubmed:articleTitle |
Dysadherin can enhance tumorigenesis by conferring properties of stem-like cells to hepatocellular carcinoma cells.
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pubmed:affiliation |
Laboratory of Tumor Suppressor, Lee Gil Ya Cancer and Diabetes Institute, Gachon University of Medicine and Science, Incheon, South Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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