rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
2010-12-20
|
pubmed:abstractText |
Essential tremor (ET) has been hypothesized to be a risk factor for the development of Parkinson disease (PD). Recently, rs9652490 variant in the leucine-rich repeat and Ig domain containing 1 gene (LINGO1) was found to be associated with ET susceptibility. To evaluate whether the same variant is associated also with PD susceptibility, we investigated the association between the LINGO1 rs9652490 variant and PD phenotype in Caucasian and Chinese PD subjects. We found no significant differences in genotypic and allele distribution between patients and control subjects (?(2)=1.931, p=0.381 for genotypic distribution; ?(2)=0.001, p=0.973 for allele distribution), suggesting this variant is not associated with PD.
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
1872-7972
|
pubmed:author |
pubmed-author:DengHaoH,
pubmed-author:DengShengS,
pubmed-author:DengXiongX,
pubmed-author:GuoYiY,
pubmed-author:JankovicJosephJ,
pubmed-author:LeWeidongW,
pubmed-author:LuoZiqiangZ,
pubmed-author:SongZhiZ,
pubmed-author:TangXiangqiX,
pubmed-author:YangHuarongH,
pubmed-author:YangYanY,
pubmed-author:ZhengWenW
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
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pubmed:issnType |
Electronic
|
pubmed:day |
7
|
pubmed:volume |
487
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
174-6
|
pubmed:meshHeading |
pubmed-meshheading:20951767-Adult,
pubmed-meshheading:20951767-Aged,
pubmed-meshheading:20951767-Alleles,
pubmed-meshheading:20951767-Asian Continental Ancestry Group,
pubmed-meshheading:20951767-Case-Control Studies,
pubmed-meshheading:20951767-European Continental Ancestry Group,
pubmed-meshheading:20951767-Female,
pubmed-meshheading:20951767-Genetic Variation,
pubmed-meshheading:20951767-Humans,
pubmed-meshheading:20951767-Male,
pubmed-meshheading:20951767-Membrane Proteins,
pubmed-meshheading:20951767-Middle Aged,
pubmed-meshheading:20951767-Nerve Tissue Proteins,
pubmed-meshheading:20951767-Parkinson Disease,
pubmed-meshheading:20951767-Phenotype
|
pubmed:year |
2011
|
pubmed:articleTitle |
LINGO1 rs9652490 variant in Parkinson disease patients.
|
pubmed:affiliation |
Department of Neurology, The Third Xiangya Hospital, Central South University, Changsha, China.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|