Linked Life Data

20951645

Source:http://linkedlifedata.com/resource/pubmed/id/20951645

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2010-11-1
pubmed:abstractText
The ability to generate functional artificial lymphoid tissue to induce specific immunity at ectopic sites could offer a potential breakthrough for treatment of diseases such as cancer and severe infection using immunotherapy. Artificial lymphoid tissue could also offer an informative tool to study further lymphoid tissue development and function in vivo. Here, we review the process of secondary and tertiary lymphoid organization, of which an understanding is essential for artificial lymphoid tissue synthesis. Using this knowledge, we consider the combination of cell types, soluble factors and scaffold properties that will enable proper accumulation and organization of lymphocytes into tissue grafts. Recent success in in vivo induction of artificial lymphoid tissue are also considered.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1471-4981
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 Elsevier Ltd. All rights reserved.
pubmed:issnType
Electronic
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
422-8
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
Synthesis of artificial lymphoid tissue with immunological function.
pubmed:affiliation
Graduate School of Medicine, Kyoto University, Yoshida-konoe machi, Sakyo-ku, Kyoto 606-8501, Japan.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't