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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2010-10-15
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pubmed:abstractText |
Pathophysiological mechanisms involved in amyotrophic lateral sclerosis (ALS) are complex and none has identified reliable markers useful in routine patient evaluation. The aim of this study was to analyze the CSF of patients with ALS by (1)H NMR (Nuclear Magnetic Resonance) spectroscopy in order to identify biomarkers in the early stages of the disease, and to evaluate the biochemical factors involved in ALS.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:AndresChristian RCR,
pubmed-author:BlascoHélèneH,
pubmed-author:CorciaPhilippeP,
pubmed-author:DevosDavidD,
pubmed-author:EmondPatrickP,
pubmed-author:FournierClémentineC,
pubmed-author:GordonPaulP,
pubmed-author:MoreauCarolineC,
pubmed-author:Nadal-DesbaratsLydieL,
pubmed-author:PradatPierre-FrançoisPF,
pubmed-author:PralineJulienJ,
pubmed-author:VeauSégolèneS,
pubmed-author:Vourc'hPatrickP
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e13223
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pubmed:meshHeading |
pubmed-meshheading:20949041-Adult,
pubmed-meshheading:20949041-Aged,
pubmed-meshheading:20949041-Aged, 80 and over,
pubmed-meshheading:20949041-Algorithms,
pubmed-meshheading:20949041-Amyotrophic Lateral Sclerosis,
pubmed-meshheading:20949041-Ascorbic Acid,
pubmed-meshheading:20949041-Case-Control Studies,
pubmed-meshheading:20949041-Discriminant Analysis,
pubmed-meshheading:20949041-Female,
pubmed-meshheading:20949041-Humans,
pubmed-meshheading:20949041-Magnetic Resonance Spectroscopy,
pubmed-meshheading:20949041-Male,
pubmed-meshheading:20949041-Metabolomics,
pubmed-meshheading:20949041-Middle Aged,
pubmed-meshheading:20949041-Principal Component Analysis,
pubmed-meshheading:20949041-Protons,
pubmed-meshheading:20949041-Pyruvates
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pubmed:year |
2010
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pubmed:articleTitle |
1H-NMR-based metabolomic profiling of CSF in early amyotrophic lateral sclerosis.
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pubmed:affiliation |
Inserm U930, CNRS 2448, Tours, France. helene.blasco@univ-tours.fr
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pubmed:publicationType |
Journal Article
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