Source:http://linkedlifedata.com/resource/pubmed/id/20949031
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
2010-10-15
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| pubmed:abstractText |
Screening tests for Trisomy 21 (T21), also known as Down syndrome, are routinely performed for the majority of pregnant women. However, current tests rely on either evaluating non-specific markers, which lead to false negative and false positive results, or on invasive tests, which while highly accurate, are expensive and carry a risk of fetal loss. We outline a novel, rapid, highly sensitive, and targeted approach to non-invasively detect fetal T21 using maternal plasma DNA.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1932-6203
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
5
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
e13184
|
| pubmed:meshHeading |
pubmed-meshheading:20949031-Down Syndrome,
pubmed-meshheading:20949031-Female,
pubmed-meshheading:20949031-Haplotypes,
pubmed-meshheading:20949031-Humans,
pubmed-meshheading:20949031-Polymerase Chain Reaction,
pubmed-meshheading:20949031-Polymorphism, Single Nucleotide,
pubmed-meshheading:20949031-Pregnancy,
pubmed-meshheading:20949031-Prenatal Diagnosis
|
| pubmed:year |
2010
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| pubmed:articleTitle |
Non-invasive prenatal detection of trisomy 21 using tandem single nucleotide polymorphisms.
|
| pubmed:affiliation |
Division of Cardiothoracic Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.
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| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|