Source:http://linkedlifedata.com/resource/pubmed/id/20948629
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
2010-10-15
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| pubmed:abstractText |
In recent studies, two distinct mechanisms have been proposed to account for major histocompatibility complex (MHC) restriction of T-cell activity: (a) evolution-driven interactions between T-cell receptor (TCR) variable regions and MHC, and (b) a requirement for CD4 or CD8 binding to MHC to initiate signalling through the TCR complex. Both mechanisms are likely to be essential, but for different reasons.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:status |
PubMed-not-MEDLINE
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| pubmed:issn |
1757-594X
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| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
1
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
55
|
| pubmed:year |
2009
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| pubmed:articleTitle |
Two mechanisms that account for major histocompatibility complex restriction of T cells.
|
| pubmed:affiliation |
Department of Biochemistry, University of Illinois 600 South Mathews Avenue, Urbana-Champaign, IL 61801 USA. d-kranz@illinois.edu
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| pubmed:publicationType |
Journal Article
|