|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2010-11-25
|
|
pubmed:abstractText |
Hydrolysis of intracellular cholesterol ester (CE) is the key step in the reverse cholesterol transport in macrophage foam cells. We have recently shown that neutral cholesterol ester hydrolase (Nceh)1 and hormone-sensitive lipase (Lipe) are key regulators of this process in mouse macrophages. However, it remains unknown which enzyme is critical in human macrophages and atherosclerosis.
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1524-4571
|
|
pubmed:author |
pubmed-author:FledeliusChristianC,
pubmed-author:FukayamaMasashiM,
pubmed-author:HosokawaMasakiyoM,
pubmed-author:IgarashiMasakiM,
pubmed-author:IshibashiShunS,
pubmed-author:JacobsenPoulP,
pubmed-author:KadowakiTakashiT,
pubmed-author:KumagaiMasayoshiM,
pubmed-author:LiYongxueY,
pubmed-author:NagaiRyozoR,
pubmed-author:NagashimaShuichiS,
pubmed-author:NishiMakikoM,
pubmed-author:OhashiKenK,
pubmed-author:OhtaKeisukeK,
pubmed-author:OsugaJun-ichiJ,
pubmed-author:SekiyaMotohiroM,
pubmed-author:TakahashiManabuM,
pubmed-author:TakanashiMikioM,
pubmed-author:TakaseSatoruS,
pubmed-author:UozakiHiroshiH,
pubmed-author:YagyuHiroakiH
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
26
|
|
pubmed:volume |
107
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1387-95
|
|
pubmed:dateRevised |
2011-11-3
|
|
pubmed:meshHeading |
pubmed-meshheading:20947831-Aged,
pubmed-meshheading:20947831-Aged, 80 and over,
pubmed-meshheading:20947831-Atherosclerosis,
pubmed-meshheading:20947831-Biological Transport,
pubmed-meshheading:20947831-Carrier Proteins,
pubmed-meshheading:20947831-Cells, Cultured,
pubmed-meshheading:20947831-Cholesterol,
pubmed-meshheading:20947831-Female,
pubmed-meshheading:20947831-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:20947831-Gene Knockdown Techniques,
pubmed-meshheading:20947831-HEK293 Cells,
pubmed-meshheading:20947831-Humans,
pubmed-meshheading:20947831-Macrophages,
pubmed-meshheading:20947831-Male,
pubmed-meshheading:20947831-Middle Aged,
pubmed-meshheading:20947831-Monocytes,
pubmed-meshheading:20947831-Serine Proteases,
pubmed-meshheading:20947831-Sterol Esterase
|
|
pubmed:year |
2010
|
|
pubmed:articleTitle |
The critical role of neutral cholesterol ester hydrolase 1 in cholesterol removal from human macrophages.
|
|
pubmed:affiliation |
Department of Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Japan.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
